Receptor mediated endocytosis

Endocytosis pathways[ edit ] Schematic drawing illustrating clathrin-mediated left and clathrin-independent endocytosis right of synaptic vesicle membranes. Endocytosis pathways can be subdivided into four categories: Coated pits can concentrate large extracellular molecules that have different receptors responsible for the receptor-mediated endocytosis of ligands, e.

Receptor mediated endocytosis

Are you sure you want to delete this answer? Yes Sorry, something has gone wrong. Receptor-mediated endocytosis RME is a process by which cells internalize molecules endocytosis by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being internalized.

One example of receptor-mediated endocytosis important in human physiology is the main mechanism by which cholesterol is taken up by cells, in particular, liver cells.

Cholesterol is carried in the blood primarily by low density lipoproteins LDL. In many people, the LDL receptor is defective, so uptake of cholesterol-containing LDL from the blood into liver cells is reduced and LDL-cholesterol accumulates in the blood.

This is thought to be the cause of damage to blood vessel walls, as elevated LDL levels result in their penetration into the wall of arteries and causes atherosclerotic vascular disease atherosclerosis.

Atherosclerosis is the primary cause of heart attacks and strokes. Another example of receptor-mediated endocytosis involves the actions of the cell surface transferrin receptor, which binds the iron transport protein transferrin.

In the acidic endosome, the iron is released from transferrin, and then the iron-free transferrin still bound to the transferrin receptor returns from the early endosome to the cell surface.Receptor-mediated endocytosis is a major activity of the plasma membranes of eukaryotic cells.

More than 20 different receptors have been shown to be selectively internalized by this pathway. More than 20 different receptors have been shown to be selectively internalized by this pathway. endocytosis A method by which a large molecule, such as a protein, can enter a cell.

The plasma membrane of the cell is invaginated by the molecule so that an internal vesicle is formed containing the molecule. Receptor-mediated endocytosis is a major activity of the plasma membranes of eukaryotic cells.

Receptor mediated endocytosis

More than 20 different receptors have been shown to be selectively internalized by this pathway. More than 20 different receptors have been shown to be selectively internalized by this pathway. Endocytosis is a cellular process in which substances are brought into the cell.

Phagocytosis

The material to be internalized is surrounded by an area of plasma membrane, which then buds off inside the cell to form a vesicle containing the ingested material. Endocytosis includes pinocytosis (cell drinking) and phagocytosis (cell eating). receptor mediated endocytosis uptake of materials bound to specific cell-surface receptors by invagination of the plasma membrane to form a small membrane-bounded vesicle; a mechanism for entry of viruses into cells.

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receptor mediated endocytosis uptake of materials bound to specific cell-surface receptors by invagination of the plasma membrane to form a small membrane-bounded vesicle; a mechanism for entry of viruses into cells. Receptor-mediated endocytosis is a major activity of the plasma membranes of eukaryotic cells. More than 20 different receptors have been shown to be selectively internalized by this pathway. More than 20 different receptors have been shown to be selectively internalized by this pathway. Receptor-mediated endocytosis is a major activity of the plasma membranes of eukaryotic cells. More than 20 different receptors have been shown to be selectively internalized by this pathway. More than 20 different receptors have been shown to be selectively internalized by this pathway.

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Receptor-mediated endocytosis - Wikipedia